Innovative Biomimetic Exosomes for Targeted Delivery and Enhanced Efficacy
BIOMMIMETIC EXOSOMES
Unlock the Power of Exosome-Like Technology
The exosome-like delivery nanovesicles are designed to mimic the structure and function of natural exosomes for targeted delivery of active agents.
Biomimetic Exosomes bring the best of both worlds together. They take advantage of nature wisdom by using plant extracts rich in biocompounds such as proteins and RNA that have been used since ancient times and that have solid scientific evidence backing up their activity at a cellular level.
Combining this with our latest technology and innovation in delivery systems and medical-grade manufacturing processes puts the Biomimetic Exosomes at the forefront of a cosmetic revolution.
WHAT MAKES OUR EXOSOMES UNIQUE
Our innovative exosomes are designed for unparalleled delivery and efficacy
Non-invasive penetration and specific delivery
INdermal Biomimetic Exosomes have been developed based on our vast expertise on liposome design.
Deliver your active specifically at the cosmetic target required without the need of any external mechanism, for example on the epidermis (DDS) or the follicle (FDS).
Unlike traditional exosomes that require mechanical penetration via puncture, our system penetrates the skin naturally, ensuring optimal and gradual delivery without discomfort or risk.
Highest Concentration: A million times more
Natural exosomes can be found at concentrations as low as in the order of 10^8 exosomes/ml in serum or plasma. Indermal can produce Biomimetic Exosomes in high concentration (10^14 exosomes/ml), a million times more concentrated than natural sources and so boosting their cosmetic performance.
Celular Afinity
Exosome-like vesicles show cellular affinity in the microscopy.
The exosome-like vesicles specifically target cells acting effectively as communicators like natural exosomes.
High encapsulation efficiency
With our medical background experience working with exosomes and other nanovehicles we are able to encapsulate active ingredients in the exosome-like system keeping our most demanding standards of high entrapment and loading efficiency.
Plant inspired design
INdermal Biomimetic Exosomes are enriched with natural plant extracts which set them apart from other liposome systems showcasing the synergistic effects of their contents.
They also feature β-sitosterol a phytochemical compound serving as a vegetal equivalent to cholesterol. It improves the absorption and bioavailability of the Biomimetic Exosomes, promotes skin health and helps cell targeting.
Surfaced loaded proteins
Part of the proteins and peptides contained in the exosome-like formulations are located on the surface as in nature exosomes, being able to effectively execute their actions.
This can be tested with the Z-potential of the vesicle. The change in the surface Z-potential with or without the added proteins proves that some of them are located on the membrane of the vesicle.
Biomimetic Exosomes act as natural cellular communicators, enhancing intercellular signaling
Delivers proteins, lipids, RNA, and growth factors to stimulate cellular repair and renewal
Enhances the skin's structural integrity, reducing visible signs of aging
Provides anti-inflammatory benefits to soothe and repair damaged skin
Intrincated design of the deivery vehicle
PURE PHOSPHOLIPIDS
EXOSOME PROTEINS
TARGET LIPIDS
MEMBRANE STABILIZERS
PENETRATION ENHANCERS
PLANT BIOCOMPOUNDS
EDGE ACTIVATORS
CHARGE MODULATORS
COSMETIC ACTIVE
CUSTOM BIOMIMETIC EXOSOME-LIKE PRODUCTS
We Adapt to the Specific Requirements of each Customer
Choose your target layer
Choose one ore more plant extracts to base your exosome on (preferably ones with known proteomics and genomics to decrease variability of the productions)
Optional: choose a mix of actives or a single active ingredient like a peptide to enhance the activity of the exosome
Advanced Delivery Systems for Targeted Active Ingredient Efficacy
The active ingredients encapsulated in the Follicular Delivery Systems are delivered specifically to the hair follicle for a more intense and precise effect on the structures and cells located there: the hair bulb, the dermal papilla and the sebaceous gland.